Recombinant HOMER1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant HOMER1 抗体 (ABIN7828294)
抗原
See all HOMER1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant Homer1 Monoclonal Antibody
-
纯化方法
- Protein A purified
-
免疫原
- Recombinant human Homer1 fragment
-
亚型
- IgG, kappa
-
-
anti-Homer Homolog 1 (HOMER1) (Center) antibody
HOMER1 适用: 人, 小鼠, 大鼠 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 1-354) antibodyHOMER1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) antibodyHOMER1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 1-354) antibodyHOMER1 适用: 人 WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal AT1F3 unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 101-150) antibodyHOMER1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 猴, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 1-354) antibodyHOMER1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 96-122), (N-Term) antibodyHOMER1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18229 unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 1-354) antibodyHOMER1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 281-330) antibodyHOMER1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 豚鼠, 斑马鱼, 猴, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Homer Homolog 1 (HOMER1) (AA 1-354) antibodyHOMER1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT1F3 unconjugated
-
-
应用备注
- WB 1:500-1:1000,IHC 1:200-1:1000
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- HOMER1 (Homer Homolog 1 (HOMER1))
-
别名
- Homer1
-
背景
- Vesl,HOMER,Vesl1,Homer1,Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Differentially regulates the functions of the calcium activated channel ryanodine receptors RYR1 and RYR2. Isoform 1 decreases the activity of RYR2, and increases the activity of RYR1, whereas isoform 5 counteracts the effects by competing for binding sites. Isoform 3 regulates the trafficking and surface expression of GRM5. Isoform 5 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1, isoform 2 and isoform 3 to regulate synaptic metabotropic glutamate function. Isoform 5, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 41 kDa
Observed MW: 46 kDa The actual band is not consistent with the expectation.
-
UniProt
- Q9Z2Y3
-
途径
- Skeletal Muscle Fiber Development
抗原
-
