Recombinant HOXB13 抗体
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北京 101111
Quick Overview for Recombinant HOXB13 抗体 (ABIN7828292)
抗原
See all HOXB13 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant HOXB13 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human HOXB13 fragment
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亚型
- IgG, kappa
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anti-Homeobox B13 (HOXB13) (AA 61-216) antibody
HOXB13 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E9 unconjugated
anti-Homeobox B13 (HOXB13) (AA 1-161) antibodyHOXB13 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B13 (HOXB13) antibodyHOXB13 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B13 (HOXB13) (C-Term) antibodyVerified HOXB13 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Homeobox B13 (HOXB13) (AA 82-131) antibodyHOXB13 适用: 小鼠, 大鼠, 兔, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox B13 (HOXB13) (N-Term) antibodyHOXB13 适用: 人, 小鼠, 大鼠, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-1:5000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- HOXB13 (Homeobox B13 (HOXB13))
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别名
- HOXB13
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背景
- HXB,Homeobox B,Homeo box B,Homeobox protein HoxB,Homeobox protein Hox B,Homeobox protein Hox-B,HOX B,HOXB13,PSGD,Homeo box B13,Homeobox B13,Homeobox protein Hox B13,Homeobox protein HoxB13,Homeobox protein Hox-B13,HOX B13,HOXB 13,HXB13,PSGD protein,HOXB13 is a member of the HOXB cluster which, along with the HOXA, HOXC, and HOXD clusters, governs embryonic patterning along the cranio-caudal axis. HOXB13 plays a key role in the development of the ventral prostate, where it is expressed highly from the embryonic stage through adulthood. Research studies have shown that both overexpression and RNA interference can inhibit the growth of prostate cancer cells. HOXB13 can function as a tumor suppressor by negatively regulating growth through repression of TCF4 and androgen receptor (AR) signaling. However, HOXB13 has also been shown to be overexpressed in more invasive prostate cancers, breast and ovarian cancers, and hepatocellular carcinomas. A common germline mutation G84E in the HOXB13 protein has recently been found to be associated with significant increased risk of prostate cancer. Currently, HOXB13 is being evaluated as a marker for metastatic lesions of prostate origin. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 31 kDa
Observed MW: 31 kDa
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UniProt
- Q92826
抗原
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