电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Recombinant Histone H4 抗体 (H4K12me1)

This 兔 单克隆 antibody specifically detects Histone H4 in WB, IHC, IF, IP, ChIP 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828285
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Histone H4 抗体 (H4K12me1) (ABIN7828285)

抗原

See all Histone H4 抗体
Histone H4

抗体类型

Recombinant Antibody

适用

  • 414
  • 305
  • 300
  • 17
  • 12
  • 11
  • 10
  • 10
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 441
  • 25
  • 2

克隆类型

  • 343
  • 123
  • 2
单克隆

标记

  • 235
  • 27
  • 20
  • 20
  • 20
  • 20
  • 20
  • 20
  • 7
  • 7
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
This Histone H4 antibody is un-conjugated

应用范围

  • 285
  • 143
  • 140
  • 119
  • 94
  • 66
  • 56
  • 56
  • 52
  • 47
  • 41
  • 39
  • 20
  • 12
  • 12
  • 8
  • 8
  • 6
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Flow Cytometry (FACS)

克隆位点

A838
  • 抗原表位

    • 33
    • 31
    • 28
    • 26
    • 18
    • 18
    • 17
    • 16
    • 15
    • 14
    • 14
    • 13
    • 12
    • 12
    • 11
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    H4K12me1

    原理

    Recombinant Histone H4 (Mono Methyl Lys12) Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Monomethylated human histone H4 (Lys12) peptide

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IHC 1:100-1:500,IF 1:50-1:200,FCM 1:50,ChIP 6 μg/5x106 cells,IP 1:25-1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Histone H4

    背景

    H4F,methyl histone H,methylated histone H,HIST2H,HIST1H,HISTH4H,histone H,HIST2H4B,H4/o,histone H4,HIST1H4A,FO108,H4/p,HIST1H4,Hist4h4,HISTH4H4,methyl histone H4,methylated histone H4,H4/A,H4FA,H4/I,H4FI,HIST1H4B,H4/G,H4FG,HIST1H4C,H4/B,H4FB,HIST1H4D,H4/J,H4FJ,HIST1H4E,H4/C,H4FC,HIST1H4F,H4/H,H4FH,HIST1H4H,H4/M,H4FM,HIST1H4I,H4/E,H4FE,H4/D,H4FD,HIST1H4K,H4/K,H4FK,HIST1H4L,H4/N,H4F2,H4FN,HIST2H4,HIST2H4A,H4,H4C1,H4C2,H4C3,H4C4,H4C5,H4C6,H4C8,H4C9,H4C11,H4C12,H4C13,H4C14,H4C15,H4-16,A,I,H4B,H4J,H4H,H4M,H4E,HIST1H4J,H4D,H4C,H4/p,histone H4,HIST1H4B H4/I,The amino-terminal tails of core histones undergo lysine methylation in multiple sites, termed as ""histone code"" or ""epigenetic code"". Lysine methylation in core histones is a major determinant for the formation of active and inactive regions of the genome and therefore plays vital roles in multiple cellular events. In most species, lysine methylation occurs primarily on histones H3 (Lys4, 9, 27, 36, 79) and H4 (Lys5, 8, 12, 20) and has been implicated in both transcriptional activation and silencing. Methylation in histones modulated by specific histone methyltransferases (HMTs) and histone demethylases (HDMs) is impaired in the pathologies of cancer and other diseases and therefore, enzymes regulating histone lysine methylation have become promising targets for anti-cancer drugs. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 11 kDa

    Observed MW: 11 kDa

    UniProt

    P62805
You are here: