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Recombinant Glypican 3 抗体

This 兔 单克隆 antibody specifically detects Glypican 3 in WB, IF 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7828240
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Glypican 3 抗体 (ABIN7828240)

抗原

See all Glypican 3 (GPC3) 抗体
Glypican 3 (GPC3)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Glypican 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

克隆位点

A577
  • 原理

    Recombinant Glypican-3 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Glypican-3 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:2000-1:10000,IHC 1:100-1:500,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Glypican 3 (GPC3)

    别名

    Glypican-3

    背景

    MXR,GPC,UNQ,PRO,CDw,ADAM,Protein FOAP,Secreted glypican,Glypican proteoglycan,Sialic acid-binding Ig-like lectin,C20orf,OCI,GPC3,DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1,glypican-3,CDw329,Glypican 3,Glypican proteoglycan 3,Glypican-3 [Precursor],GTR2 2,Heparan sulphate proteoglycan,Intestinal protein OCI 5,Intestinal protein OCI-5,OCI 5,Protein FOAP-9,Secreted glypican-3,Sialic acid-binding Ig-like lectin 9,SIGLEC9,Siglec-9,ADAM33,C20orf153,UNQ873,PRO1891,OCI5,Glypican 3 belongs to Glypicans (GPCs), a family of glycosylphosphatidylinositol (GPI)-anchored heparan sulphate proteoglycans (HSPGs) that may play a role in the control of cell division and growth regulation. In mammals, there are six GPCs (GPC1 to GPC6), all of which have a similar core-protein size of approx. 60 kDa and the clustering of glycosaminoglycan attachment site near the C-terminus. They are tethered to the cell surface by GPI linkages, which can be cleaved by endogenous phospholipases, thus releasing the protein. Glypican 3 (GPC3) is highly expressed in many tissues during development and plays an important role in the regulation of embryonic growth. Loss-of-function mutations of GPC3 result in the Simpson-Golabi-Behmel overgrowth syndrome (SGBS), and Gpc-3 null mice display developmental overgrowth. In hepatocellular carcinoma (HCC), the overexpression of glypican 3 has been demonstrated to be a reliable diagnostic indicator. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 70, 40 kDa

    Observed MW: 15, 70 kDa The actual band is not consistent with the expectation.

    UniProt

    P51654

    途径

    Glycosaminoglycan Metabolic Process
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