Recombinant GPX4 抗体
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北京 101111
Quick Overview for Recombinant GPX4 抗体 (ABIN7828231)
抗原
See all GPX4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Glutathione Peroxidase 4 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Glutathione Peroxidase 4 fragment
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亚型
- IgG, kappa
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anti-Glutathione Peroxidase 4 (GPX4) (AA 30-197) antibody
GPX4 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibodyGPX4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) antibodyKD Validated GPX4 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 25GB2980 unconjugated Recombinant Antibody
anti-Glutathione Peroxidase 4 (GPX4) (C-Term) antibodyVerified GPX4 适用: 人 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 74-197) antibodyGPX4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 72-121) antibodyGPX4 适用: 人, 小鼠, 大鼠, 斑马鱼, 豚鼠, Cow, 猴, 山羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) (AA 81-93) antibodyGPX4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutathione Peroxidase 4 (GPX4) antibodyGPX4 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- GPX4 (Glutathione Peroxidase 4 (GPX4))
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别名
- Glutathione Peroxidase 4
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背景
- Glutathione peroxidase,GSHPx,GPx,GPX4,GPx-4,GSHPx-4,MCSP,PHGPx,SMDS,snGPx,snPHGPx,glutathione peroxidase 4,glutathione peroxidase 4,GPx-4,GSHPx-4,MCSP,PHGPx,SMDS,snGPx,snPHGPx,The selenoprotein glutathione peroxidase 4 (GPX4) is a master regulator of ferroptosis, a form of programmed cell death induced by iron-dependent lipid peroxidation. GPX4 converts lipid hydroperoxides to non-toxic lipid alcohols, therefore preventing ferroptosis. Research studies show that selenium enhances GPX4 expression and inhibits ferroptotic death to protect neurons. In addition, some therapy-resistant cancer cells depend on GPX4 to survive. Loss of GPX4 leads to ferroptosis and thus prevents tumor relapse in mice. Furthermore, redox homeostasis mediated by GPX4 is essential for activation of the cytosolic DNA-sensing cGAS-STING pathway and initiation of the subsequent innate immune response. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 22 kDa
Observed MW: 22 kDa
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UniProt
- P36969
抗原
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