Recombinant FGL1 抗体
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北京 101111
Quick Overview for Recombinant FGL1 抗体 (ABIN7828204)
抗原
See all FGL1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant FGL1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human FGL1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000,IHC 1:50-1:200
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- FGL1 (Fibrinogen-Like 1 (FGL1))
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别名
- FGL1
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背景
- FGL,Fibrinogen-like protein,Liver fibrinogen-related protein,LFIRE,HP-041,Hepassocin,HPS,HFREP-1,LFIRE-1,HFREP1,Fibrinogen-like protein 1,Liver fibrinogen-related protein 1,FGL1,Fgl1,Hepassocin,HFREP1,HFREP-1,FGL 1,Fibrinogen like 1,Fibrinogen like protein 1,Fibrinogen related protein 1,Hepatocellular carcinoma related sequence,Hepatocyte derived fibrinogen related protein 1,Hepatocyte-derived fibrinogen-related protein 1,HFREP 1,HP 041,HP041,LFIRE 1,LFIRE1,Liver fibrinogen related protein 1,MFIRE 1,MGC108569,MGC12455,MGC37822,OTTHUMP00000122468,Fibrinogen-like protein 1 (FGL1), also known as hepassocin, is a secreted protein mainly expressed in liver and its expression is further enhanced following acute liver injury. FGL1 null mice have multiple metabolic abnormalities and are more prone to develop hepatocellular carcinoma under certain experimental conditions, suggesting FGL1 has diverse functions in vivo. More recently, FGL1 was found to be highly expressed in human cancer cells and function as an inhibitory ligand for LAG3. Blockade of the FGL1-LAG3 interaction stimulates tumor immunity in mouse models. In addition, a high plasma FGL1 level in human cancer patients is associated with a poor prognosis and resistance to anti-PD-1/PD-L1 immunotherapy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 36 kDa
Observed MW: 34 kDa The actual band is not consistent with the expectation.
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UniProt
- Q08830
抗原
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