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Recombinant FGL1 抗体

This 兔 单克隆 antibody specifically detects FGL1 in WB 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7828204
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant FGL1 抗体 (ABIN7828204)

抗原

See all FGL1 抗体
FGL1 (Fibrinogen-Like 1 (FGL1))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This FGL1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A637
  • 原理

    Recombinant FGL1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human FGL1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:50-1:200

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    FGL1 (Fibrinogen-Like 1 (FGL1))

    别名

    FGL1

    背景

    FGL,Fibrinogen-like protein,Liver fibrinogen-related protein,LFIRE,HP-041,Hepassocin,HPS,HFREP-1,LFIRE-1,HFREP1,Fibrinogen-like protein 1,Liver fibrinogen-related protein 1,FGL1,Fgl1,Hepassocin,HFREP1,HFREP-1,FGL 1,Fibrinogen like 1,Fibrinogen like protein 1,Fibrinogen related protein 1,Hepatocellular carcinoma related sequence,Hepatocyte derived fibrinogen related protein 1,Hepatocyte-derived fibrinogen-related protein 1,HFREP 1,HP 041,HP041,LFIRE 1,LFIRE1,Liver fibrinogen related protein 1,MFIRE 1,MGC108569,MGC12455,MGC37822,OTTHUMP00000122468,Fibrinogen-like protein 1 (FGL1), also known as hepassocin, is a secreted protein mainly expressed in liver and its expression is further enhanced following acute liver injury. FGL1 null mice have multiple metabolic abnormalities and are more prone to develop hepatocellular carcinoma under certain experimental conditions, suggesting FGL1 has diverse functions in vivo. More recently, FGL1 was found to be highly expressed in human cancer cells and function as an inhibitory ligand for LAG3. Blockade of the FGL1-LAG3 interaction stimulates tumor immunity in mouse models. In addition, a high plasma FGL1 level in human cancer patients is associated with a poor prognosis and resistance to anti-PD-1/PD-L1 immunotherapy. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 36 kDa

    Observed MW: 34 kDa The actual band is not consistent with the expectation.

    UniProt

    Q08830
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