Recombinant EIF4G1 抗体
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北京 101111
Quick Overview for Recombinant EIF4G1 抗体 (ABIN7828190)
抗原
See all EIF4G1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant eIF4G1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human eIF4G1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000,IHC 1:500-1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
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别名
- eIF4G1
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背景
- PARK,DKFZp686A,eIF 4 gamma,eIF-4-gamma,Eukaryotic translation initiation factor 4 gamma,IF4G,EIF4G1,EIF-4G1,EIF4F,EIF4G,EIF4GI,P220,PARK18,DKFZp686A1451,eIF 4 gamma 1,eIF 4G 1,eIF 4G1,EIF4 gamma,eIF-4G 1,eIF-4-gamma 1,Eukaryotic translation initiation factor 4 gamma 1,IF4G1,The initiation of translation is an important biological event and a variety of factors contribute to this process. Members of the eIF4 translation initiation factor family bind to the 5' m7GTP mRNA cap and unwind the mRNA secondary structure. The amino-terminal portion of eIF4G physically associates with eIF4E to stimulate the binding of eIF4E to the mRNA cap structure. eIF4G also interacts with eIF3 and eIF4A and serves as an adaptor molecule in the eIF4 complex. Moreover, eIF4G plays a role in internal ribosomal entry site (IRES)-mediated initiation of translation. The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII). These factors share a homologous sequence that provides for interaction with initiation factors eIF3 and eIF4A. Both eIF4G1 and eIF4G3 are involved in cap-dependent translation, while eIF4G2 plays a role in IRES-mediated translation of some genes during cell stress. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 175 kDa
Observed MW: 250 kDa The actual band is not consistent with the expectation.
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UniProt
- Q04637
抗原
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