Recombinant EIF3G 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant EIF3G 抗体 (ABIN7828189)
抗原
See all EIF3G 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant eIF3G Monoclonal Antibody
-
纯化方法
- Protein A purified
-
亚型
- IgG, kappa
-
-
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (Middle Region) antibody
EIF3G 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼, 山羊 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 1-320) antibodyEIF3G 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 2-320) antibodyEIF3G 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 51-150) antibodyEIF3G 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 200-250) antibodyEIF3G 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 50-100) antibodyEIF3G 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 42-91) antibodyEIF3G 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 斑马鱼, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (N-Term) antibodyEIF3G 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 209-238) antibodyEIF3G 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26846 unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) antibodyEIF3G 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:1000-1:2000,IHC 1:50-1:100,IF 1:50-1:100,FCM 1:50
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))
-
别名
- eIF3G
-
背景
- EIF3S,EIF3G,EIF3-P42,EIF3S4,eIF3-delta,eIF3-p44,eIF3 is a large translation initiation complex with 10 to 13 different subunits. eIF3A, eIF3B, eIF3C, eIF3E, eIF3F, and eIF3H are the core subunits critical for the function of this complex. eIF3 physically interacts with eIF4G, which may be responsible for the association of the 40S ribosomal subunit with mRNA. eIF3 also stabilizes the binding of Met-tRNAf.eIF2.GTP to the 40S ribosomal subunit and helps keep the integrity of the resulting complex upon addition of the 60S ribosomal subunit. Studies have shown that mTOR interacts with eIF3 directly. When cells are stimulated by hormones or mitogenic signals, mTOR binds to the eIF3 complex and phosphorylates S6K1. This process results in the dissociation of S6K1 from eIF3 and S6K1 activation. The activated S6K1 then phosphorylates its downstream targets including ribosomal protein S6 and eIF4B, resulting in stimulation of translation. Further findings demonstrated that activated mTOR signaling induces the association of eIF3 with eIF4G upon stimulation with insulin. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 36 kDa
Observed MW: 40 kDa The actual band is not consistent with the expectation.
-
UniProt
- O75821
-
途径
- Ribonucleoprotein Complex Subunit Organization
抗原
-
