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Recombinant EIF3B 抗体

The 兔 单克隆 anti-EIF3B antibody (Clone A212) (ABIN7828188) specifically detects EIF3B in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828188
发货至: 中国
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Quick Overview for Recombinant EIF3B 抗体 (ABIN7828188)

抗原

See all EIF3B 抗体
EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

抗体类型

Recombinant Antibody

适用

  • 47
  • 19
  • 16
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 47

克隆类型

  • 24
  • 23
单克隆

标记

  • 22
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
This EIF3B antibody is un-conjugated

应用范围

  • 37
  • 15
  • 14
  • 13
  • 12
  • 11
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A212
  • 原理

    Recombinant eIF3B Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human eIF3B1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))

    别名

    eIF3B

    背景

    PRT,EIF3S,EIF3B,EIF3-ETA,EIF3-P110,EIF3-P116,EIF3S9,PRT1,RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. UniRule annotation4 Publications (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 92 kDa

    Observed MW: 116 kDa The actual band is not consistent with the expectation.

    UniProt

    P55884

    途径

    Ribonucleoprotein Complex Subunit Organization
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