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Recombinant EED 抗体

This 兔 单克隆 antibody specifically detects EED in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7828174
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant EED 抗体 (ABIN7828174)

抗原

See all EED 抗体
EED (Embryonic Ectoderm Development (EED))

抗体类型

Recombinant Antibody

适用

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人, 小鼠

宿主

  • 50
  • 7
  • 2

克隆类型

  • 54
  • 5
单克隆

标记

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This EED antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

A755
  • 原理

    Recombinant EED Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    EED (Embryonic Ectoderm Development (EED))

    别名

    EED

    背景

    WAIT,EED,HEED,WAIT1,COGIS,embryonic ectoderm development,HWAIT1,The polycomb group (PcG) proteins contribute to the maintenance of cell identity, stem cell self-renewal, cell cycle regulation and oncogenesis by maintaining the silenced state of genes that promote cell lineage specification, cell death and cell-cycle arrest. PcG proteins exist in two complexes that cooperate to maintain long-term gene silencing through epigenetic chromatin modifications. The first complex, EED-EZH2, is recruited to genes by DNA-binding transcription factors and methylates histone H3 on Lys27. Methylation of Lys27 facilitates the recruitment of the second complex, PRC1, which ubiquitinylates histone H2A on Lys119. Embryonic ectoderm development protein (EED) is a component of the PRC2 complex, which together with Ezh2 and SUZ12 is absolutely required for histone methyl-transferase activity. EED, SUZ12 and EZH2 are overexpressed in various types of cancer, including tumors of the colon, breast, prostate and ovary. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 50 kDa

    Observed MW: 50-70 kDa The actual band is not consistent with the expectation.

    UniProt

    O75530
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