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Recombinant ELP3/KAT9 抗体

The 兔 单克隆 anti-ELP3/KAT9 antibody (Clone A272) (ABIN7828173) specifically detects ELP3/KAT9 in WB, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828173
发货至: 中国
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Quick Overview for Recombinant ELP3/KAT9 抗体 (ABIN7828173)

抗原

See all ELP3/KAT9 (ELP3) 抗体
ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

抗体类型

Recombinant Antibody

适用

  • 52
  • 25
  • 14
  • 1
人, 小鼠, 大鼠

宿主

  • 49
  • 4

克隆类型

  • 39
  • 14
单克隆

标记

  • 33
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This ELP3/KAT9 antibody is un-conjugated

应用范围

  • 39
  • 17
  • 15
  • 12
  • 11
  • 10
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

A272
  • 原理

    Recombinant ELP3 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human ELP3 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

    别名

    ELP3

    背景

    ELP,KAT,ELP3,KAT9,Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. May also act as a protein lysine acetyltransferase by mediating acetylation of target proteins, such activity is however unclear in vivo and recent evidences suggest that ELP3 primarily acts as a tRNA acetyltransferase. Involved in neurogenesis: regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation. Required for acetylation of GJA1 in the developing cerebral cortex. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 62 kDa

    Observed MW: 62 kDa

    UniProt

    Q9H9T3
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