Recombinant ENPP1 抗体
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北京 101111
Quick Overview for Recombinant ENPP1 抗体 (ABIN7828169)
抗原
See all ENPP1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant ENPP1/PC1 Monoclonal Antibody
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纯化方法
- Protein A purified
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亚型
- IgG, kappa
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应用备注
- WB 1:2000-1:5000,IHC 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))
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别名
- ENPP1/PC1
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背景
- M6S,PDNP,Enpp,M6S1,NPPS,PC1,PDNP1,ENPP1,Ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) is a single-pass, type II transmembrane protein primarily involved in ATP hydrolysis at the plasma membrane. Targeting of ENPP1 to the basolateral cell surface relies on the presence of a carboxy-terminal di leucine-based signal. ENPP1 plays important roles in bone mineralization and soft tissue calcification. Mutations in the corresponding ENPP1 gene cause generalized arterial calcification in infancy (GACI) and idiopathic infantile arterial calcification (IIAC). ENPP1 inhibits insulin receptor function and overexpression of this enzyme causes insulin resistance and glucose intolerance in mice. Genetic variants of ENPP1 have been associated with obesity and type 2 diabetes. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 105 kDa
Observed MW: 130 kDa The actual band is not consistent with the expectation.
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UniProt
- P22413
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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