Recombinant CD39 抗体
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北京 101111
Quick Overview for Recombinant CD39 抗体 (ABIN7828168)
抗原
See all CD39 (ENTPD1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CD39 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CD39 (ENTPD1) (Ectonucleoside Triphosphate diphosphohydrolase 1 (ENTPD1))
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别名
- CD39
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背景
- SPG,Ecto-ATP diphosphohydrolase,Ectonucleoside triphosphate diphosphohydrolase,ENTPD,ENTPD1,ATPDase,CD39,NTPDase-1,SPG64,CD 39,NTPDase1,Ecto-apyrase,Ectonucleoside triphosphate diphosphohydrolase 1,NTPDase 1,Ecto-ATP diphosphohydrolase 1,Lymphoid cell activation antigen,NTPDase-1,CD39 antigen,DKFZp686D194,DKFZp686I093,Ecto apyrase,Ecto ATP diphosphohydrolase,Ecto-ATPase 1,Ecto-ATPDase 1,ENTP1,ENTPD 1,FLJ40921,FLJ40959,CD39,also known as ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), is a multi-pass membrane ectoenzyme that metabolizes adenosine-5'-triphosphate (ATP) to regulate purinergic signaling. Purinergic signaling by extracellular ATP and its metabolites regulate many biological processes, including vascular tone, digestion, neuronal function, and inflammation in both normal and diseased states. CD39 is expressed in endothelial cells in the vasculature to regulate local platelet purinergic signaling via metabolism of ATP to adenosine. Accordingly, CD39 regulates platelet activation aggregation and contributes to the antithrombotic properties of endothelial cells. ATP and its metabolites also finely modulate the activity of T cells and macrophages. Immunomodulation is regulated, in part, by the availability of extracellular ATP and adenosine, suggesting that CD39 may play an immunosuppressive role in the tumor microenvironment. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 58 kDa
Observed MW: 78 kDa The actual band is not consistent with the expectation.
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UniProt
- P49961
抗原
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