Recombinant EGR2 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant EGR2 抗体 (ABIN7828167)
抗原
See all EGR2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant EGR2 Monoclonal Antibody
-
纯化方法
- Protein A purified
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- WB 1:1000
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- EGR2 (Early Growth Response 2 (EGR2))
-
别名
- EGR2
-
背景
- EGR,KROX,EGR2,AT591,CMT1D,CMT4E,KROX20,DKFZp686J1957,Drosophila,E3 SUMO-protein ligase EGR2,early growth response 2,Early growth response protein 2,EGR-2,FLJ14547,homolog (early growth response-2),KROX 20 Drosophila homolog,Krox 20 homolog Drosophila,KROX-20,Krox20 protein,Zinc finger protein Krox-20,EGR2 is also named as KROX20, belongs to the EGR C2H2-type zinc-finger protein family. As a zinc finger transcription factor, it is observed in both the somata and dendrites of central neurons. EGR2 plays an important role in the transient formation of hindbrain developmental compartments or rhombomeres and is also an important factor in peripheral myelination, maintenance of synaptic plasticity and long-term potentiation. EGR2 expression is induced downstream of TCR signaling in NKT precursors and EGR2 is directly connected with the key molecular checkpoints defining NKT lineage commitment and stage progression, suggesting that EGR2 not only induces the early lineage-defining transcription factor PLZF, but also controls the downstream expression of the IL-2Rβ chain. EGR2 is regulated by both soluble and membrane-bound neuregulins and its concentration is partially modulated by calcium-dependent events. EGR2/Krox20 is also required for induction of Pmp22, and is nuclear-localized. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 50 kDa
Observed MW: 55 kDa The actual band is not consistent with the expectation.
-
UniProt
- P11161
抗原
-