Recombinant DPP4 抗体
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北京 101111
Quick Overview for Recombinant DPP4 抗体 (ABIN7828156)
抗原
See all DPP4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant DPP4/CD26 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human DPP4/CD26 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:200-1:500
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- DPP4 (Dipeptidyl-Peptidase 4 (DPP4))
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别名
- DPP4/CD26
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背景
- DPP,dipeptidylpeptidase,dipeptidyl-peptidase,dipeptidyl peptidase,T-cell activation antigen CD,adenosine deaminase complexing protein,DPP4,ADABP,ADCP2,CD26,DPPIV,TP103,Dipeptidyl peptidase IV,ADCP-2,dipeptidyl-peptidase 4,dipeptidyl peptidase 4,DPP IV,dipeptidylpeptidase 4,T-cell activation antigen CD26,adenosine deaminase complexing protein 2,dipeptidylpeptidase IV,Dipeptidyl peptidase IV (DPP IV),ADABP Protein,ADCP2 Protein,CD26 Protein,DPPIV Protein,Human,TP103 Protein,DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding domain are located in the extracellular fragment. DPP4/CD26 is a multifunctional protein that exists in both a membrane bound form as well as an extracellular soluble form. As a peptidase, it removes N-terminal dipeptides sequentially from proteins with a proline or alanine as the penultimate P1 amino acid. DPP4/CD26 has been shown to cleave a wide range of substrates including GLP-1, BNP, etc. In addition to its peptidase activity, DPP4/CD26 interacts with multiple important cell surface ligands, such as adenosine deaminase, fibronectin, and IGF2 receptor to influence processes like T cell activation, cell migration and proliferation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 110 kDa
Observed MW: 110 kDa
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UniProt
- P27487
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途径
- Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
抗原
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