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Recombinant CIRBP 抗体

The 兔 单克隆 anti-CIRBP antibody (Clone A731) (ABIN7828125) specifically detects CIRBP in WB, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7828125
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CIRBP 抗体 (ABIN7828125)

抗原

See all CIRBP 抗体
CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CIRBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

A731
  • 原理

    Recombinant CIRBP Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:500-1:1000,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

    别名

    CIRBP

    背景

    CIRBP,CIRP,A18HNRNP,Cold-induced RNA-binding protein (CIRBP) is a 172-residue, multifunctional sensor protein that was first isolated as a protein induced in mouse fibroblasts cultured at 32 °C. Conversely, CIRBP expression decreases in cells or tissues subjected to increased temperature. The CIRBP protein is composed of an amino-terminal RNA-binding domain and a carboxyl-terminal, glycine-rich domain. Stressful stimuli, such as hypoxia, heat shock, osmotic shock, or oxidative conditions, lead to translocation of CIRBP from the nucleus to cytoplasmic stress granules through a mechanism involving CIRBP methylation-dependent nuclear export. CIRBP plays a role in regulating apoptosis and preserving the stemness of neural stem cells at moderately low temperatures. Research studies demonstrate that CIRBP contributes to the regulation of circadian rhythm through post-translational modulation of CLOCK expression. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 19 kDa

    Observed MW: 16 kDa The actual band is not consistent with the expectation.

    UniProt

    Q14011

    途径

    Ribonucleoprotein Complex Subunit Organization
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