Recombinant CHD4 抗体
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北京 101111
Quick Overview for Recombinant CHD4 抗体 (ABIN7828114)
抗原
See all CHD4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CHD4 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CHD4 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-3000,IHC 1:50-100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
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别名
- CHD4
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背景
- CHD,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES,Chromodomain helicase DNA-binding protein 4 (CHD4) is an ATP dependent chromatin remodeler and a major subunit of the repressive NuRD complex. This complex plays key roles in transcriptional regulation and reorganization and maintenance of chromatin structure, as it targets pericentromeric heterochromatin and has recently been implicated in DNA damage repair, being rapidly recruited to DNA double strand breaks. CHD4 is a novel BRIT1 binding partner that regulates the HR repair process, which is a critical pathway of repairing DNA double strand breaks and plays an essential role in maintaining genomic integrity. The calculated molecular weight of CHD4 is 218 kDa, but modified CHD4 is about 250-280 kDa. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 218 kDa
Observed MW: 280 kDa The actual band is not consistent with the expectation.
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UniProt
- Q14839
抗原
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