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Recombinant CHD4 抗体

This 兔 单克隆 antibody specifically detects CHD4 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7828114
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CHD4 抗体 (ABIN7828114)

抗原

See all CHD4 抗体
CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 44
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克隆类型

  • 35
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单克隆

标记

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This CHD4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A649
  • 原理

    Recombinant CHD4 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human CHD4 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000-3000,IHC 1:50-100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))

    别名

    CHD4

    背景

    CHD,CHD4,CHD-4,Mi-2b,Mi2-BETA,SIHIWES,Chromodomain helicase DNA-binding protein 4 (CHD4) is an ATP dependent chromatin remodeler and a major subunit of the repressive NuRD complex. This complex plays key roles in transcriptional regulation and reorganization and maintenance of chromatin structure, as it targets pericentromeric heterochromatin and has recently been implicated in DNA damage repair, being rapidly recruited to DNA double strand breaks. CHD4 is a novel BRIT1 binding partner that regulates the HR repair process, which is a critical pathway of repairing DNA double strand breaks and plays an essential role in maintaining genomic integrity. The calculated molecular weight of CHD4 is 218 kDa, but modified CHD4 is about 250-280 kDa. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 218 kDa

    Observed MW: 280 kDa The actual band is not consistent with the expectation.

    UniProt

    Q14839
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