Recombinant CENPA 抗体
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北京 101111
Quick Overview for Recombinant CENPA 抗体 (ABIN7828101)
抗原
See all CENPA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CENP-A Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CENP-A fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000,IHC 1:100-1:1000,IF 1:50,FCM 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CENPA (Centromere Protein A (CENPA))
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别名
- CENP-A
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背景
- CenH,CENPA,CENP-A,CenH3,Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore .The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3.May serve as an epigenetic mark that propagates centromere identity through replication and cell division.Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 16 kDa
Observed MW: 18 kDa The actual band is not consistent with the expectation.
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UniProt
- P49450
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途径
- Chromatin Binding, Maintenance of Protein Location
抗原
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