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Recombinant CENPA 抗体

The 兔 单克隆 anti-CENPA antibody (Clone A184) (ABIN7828101) specifically detects CENPA in WB, IF, IHC 和 FACS. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7828101
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CENPA 抗体 (ABIN7828101)

抗原

See all CENPA 抗体
CENPA (Centromere Protein A (CENPA))

抗体类型

Recombinant Antibody

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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单克隆

标记

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This CENPA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

A184
  • 原理

    Recombinant CENP-A Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human CENP-A fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000,IHC 1:100-1:1000,IF 1:50,FCM 1:50-1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CENPA (Centromere Protein A (CENPA))

    别名

    CENP-A

    背景

    CenH,CENPA,CENP-A,CenH3,Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore .The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3.May serve as an epigenetic mark that propagates centromere identity through replication and cell division.Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 16 kDa

    Observed MW: 18 kDa The actual band is not consistent with the expectation.

    UniProt

    P49450

    途径

    Chromatin Binding, Maintenance of Protein Location
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