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Recombinant CDC25C 抗体

The 兔 单克隆 anti-CDC25C antibody (Clone A595) (ABIN7828098) specifically detects CDC25C in WB. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828098
发货至: 中国
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北京 101111
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Quick Overview for Recombinant CDC25C 抗体 (ABIN7828098)

抗原

See all CDC25C 抗体
CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

抗体类型

Recombinant Antibody

适用

  • 126
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  • 1
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 112
  • 16

克隆类型

  • 98
  • 30
单克隆

标记

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  • 1
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This CDC25C antibody is un-conjugated

应用范围

  • 104
  • 51
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  • 30
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  • 10
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  • 2
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Western Blotting (WB)

克隆位点

A595
  • 原理

    Recombinant Cdc25C Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Cdc25C fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

    别名

    Cdc25C

    背景

    CDC,PPP1R,CDC25C,CDC25,PPP1R60,Cdc25C is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic cells into mitosis. Cdc25C is constitutively phosphorylated at Ser216 throughout interphase by c-TAK1, while phosphorylation at this site is DNA damage-dependent at the G2/M checkpoint. When phosphorylated at Ser216, Cdc25C binds to members of the 14-3-3 family of proteins, sequestering Cdc25C in the cytoplasm and thereby preventing premature mitosis. The checkpoint kinases Chk1 and Chk2 phosphorylate Cdc25C at Ser216 in response to DNA damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 53 kDa

    Observed MW: 53 kDa

    UniProt

    P30307

    途径

    Cell Division Cycle, M Phase
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