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Recombinant CD8B 抗体

The 兔 单克隆 anti-CD8B antibody (Clone A702) (ABIN7828095) specifically detects CD8B in WB 和 IHC. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7828095
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD8B 抗体 (ABIN7828095)

抗原

See all CD8B 抗体
CD8B (CD8b Molecule (CD8B))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

  • 72
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克隆类型

  • 89
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单克隆

标记

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This CD8B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A702
  • 原理

    Recombinant CD8 beta Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:100

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CD8B (CD8b Molecule (CD8B))

    别名

    CD8 beta

    背景

    LYT,LEU,CD8B,CD8B1,LEU2,LY3,LYT3,P37,T-Cell Surface Glycoprotein CD8 Beta Chain,CD8,Lyt3,Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. On T cells, CD8 is the coreceptor for the T cell receptor (TCR), and these two distinct structures recognize the Antigen-Major Histocompatibility Complex (MHC). Specifically, the Ig-like domain of CD8α interacts with the α3-domain of the MHC class I molecule. CD8 ensures specificity of the TCR-antigen interaction, prolongs the contact between the T cell and the antigen presenting cell, and the α chain recruits the tyrosine kinase Lck, which is essential for T cell activation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 24 kDa

    Observed MW: 28-32 kDa The actual band is not consistent with the expectation.

    UniProt

    P10966

    途径

    TCR Signaling
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