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Recombinant CD3G 抗体

The 兔 单克隆 anti-CD3G antibody (Clone A172) (ABIN7828083) specifically detects CD3G in WB, IHC, IP 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7828083
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD3G 抗体 (ABIN7828083)

抗原

See all CD3G 抗体
CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD3G antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

克隆位点

A172
  • 原理

    Recombinant CD3G Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human CD3G fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IHC 1:500-1:2000,IF 1:50,IP 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    CD3G (CD3g Molecule, gamma (CD3-TCR Complex) (CD3G))

    别名

    CD3G

    背景

    T3G,CD3G,T3,CD_antigen: CD3g,CD3g molecule,CD3-GAMMA,IMD17,T-cell receptor T3 gamma chain,T-cell surface glycoprotein CD3 gamma chain,Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 20 kDa

    Observed MW: 18-28 kDa The actual band is not consistent with the expectation.

    UniProt

    P09693

    途径

    TCR Signaling, CXCR4-mediated Signaling Events
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