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Recombinant Caveolin 3 抗体

The 兔 单克隆 anti-Caveolin 3 antibody is suitable to detect Caveolin 3 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IHC.
产品编号 ABIN7828073
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Caveolin 3 抗体 (ABIN7828073)

抗原

See all Caveolin 3 (CAV3) 抗体
Caveolin 3 (CAV3)

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

  • 52
  • 8
  • 1

克隆类型

  • 37
  • 24
单克隆

标记

  • 25
  • 4
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  • 2
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This Caveolin 3 antibody is un-conjugated

应用范围

  • 41
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A631
  • 原理

    Recombinant Caveolin-3 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Caveolin-3 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:100-1:400

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    Caveolin 3 (CAV3)

    别名

    Caveolin-3

    背景

    LQT,CAV,VIP,CAV3,LGMD1C,LQT9,VIP-21,VIP21,Caveolin 3,Caveolin-3,M-caveolin,MGC126100,MGC126101,MGC126129,OTTHUMP00000115603,OTTHUMP00000207105,VIP 21,The 21-24 kDa integral proteins, caveolins, are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified with different tissue distributions. Caveolins form hetero- and homo-oligomers that interact with cholesterol and other lipids. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease. Caveolins interact with multiple signaling molecules, such as Gα subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS. It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Phosphorylation at Tyr14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, such as GRB7. Phosphorylation at Ser80 regulates caveolin binding to the ER membrane and entry into the secretory pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 17 kDa

    Observed MW: 17 kDa

    UniProt

    P56539

    途径

    Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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