Recombinant Caveolin-1 抗体 (pTyr14)
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Quick Overview for Recombinant Caveolin-1 抗体 (pTyr14) (ABIN7828072)
抗原
See all Caveolin-1 (CAV1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr14
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原理
- Recombinant Phospho-Caveolin-1 (Tyr14) Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- phosphorylated human Caveolin-1 (Tyr14) peptide
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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别名
- Caveolin-1
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背景
- PPH,CGL,BSCL,MSTP,cell growth-inhibiting protein,OTTHUMP,VIP,BSCL3,CGL3,LCCNS,MSTP085,PPH3,VIP21,CAV1,22 kD,caveolae protein,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22 kDa,Caveolin1,Caveolin-1,cell growth-inhibiting protein 32,OTTHUMP00000025031,VIP 21,CAV,Caveolins are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified with different tissue distributions. Caveolins form hetero- and homo-oligomers that interact with cholesterol and other lipids. Caveolins are involved in diverse biological functions, including vesicular trafficking, cholesterol homeostasis, cell adhesion, and apoptosis, and are also implicated in neurodegenerative disease. Caveolins interact with multiple signaling molecules, such as Gα subunit, tyrosine kinase receptors, PKCs, Src family tyrosine kinases, and eNOS. It is believed that caveolins serve as scaffolding proteins for the integration of signal transduction. Phosphorylation at Tyr14 is essential for caveolin association with SH2 or PTB domain-containing adaptor proteins, such as GRB7. Phosphorylation at Ser80 regulates caveolin binding to the ER membrane and entry into the secretory pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 20 kDa
Observed MW: 22 kDa The actual band is not consistent with the expectation.
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UniProt
- Q03135
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途径
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
抗原
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