Recombinant CPT1B 抗体
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北京 101111
Quick Overview for Recombinant CPT1B 抗体 (ABIN7828065)
抗原
See all CPT1B 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant CPT1B Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human CPT1B fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:5000,IHC 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))
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别名
- CPT1B
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背景
- KIAA,KIAA1670,CPT1B,CPT I,CPT1-M,CPTI-M,Carnitine palmitoyltransferase-1 (CPT1), localized to the mitochondrial outer membrane, translocates fatty acids across the mitochondrial membranes and catalyzes the rate-limiting step of β-oxidation. There are three isoforms of this enzyme: CPT1A (liver), CPT1B (muscle), and CPT1C (brain). Deficiency of CPT1A results in an autosomal recessive mitochondrial fatty acid oxidation disorder. Studies have shown that physiological high blood glucose and insulin levels inhibit CPT1B activity in human muscle and therefore divert long-chain fatty acids toward storage in human muscle as triglycerides. Furthermore, mice deficient in CPT1C show less food intake and reduced body weight. These findings suggest that CPT1 may play a role in metabolic syndromes. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 87 kDa
Observed MW: 87 kDa
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UniProt
- Q92523
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途径
- AMPK Signaling, Monocarboxylic Acid Catabolic Process
抗原
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