Recombinant BCL6 抗体
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北京 101111
Quick Overview for Recombinant BCL6 抗体 (ABIN7828037)
抗原
See all BCL6 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant BCL6 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human BCL6 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:1000-1:5000,IHC 1:100-1:500
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
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别名
- BCL6
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背景
- ZNF,LAZ,ZBTB,BCL,BCL6,BCL5,BCL6A,LAZ3,ZBTB27,ZNF51,Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 79 kDa
Observed MW: 78 kDa The actual band is not consistent with the expectation.
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UniProt
- P41182
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途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
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