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Recombinant BCL6 抗体

The 兔 单克隆 anti-BCL6 antibody is suitable to detect BCL6 in samples from 人. It has been validated for IHC 和 WB.
产品编号 ABIN7828037
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant BCL6 抗体 (ABIN7828037)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB)

克隆位点

A139
  • 原理

    Recombinant BCL6 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human BCL6 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000-1:5000,IHC 1:100-1:500

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    BCL6

    背景

    ZNF,LAZ,ZBTB,BCL,BCL6,BCL5,BCL6A,LAZ3,ZBTB27,ZNF51,Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. In response to genotoxic stress, controls cell cycle arrest in GC B-cells in both p53/TP53-dependedent and -independent manners. Besides, also controls neurogenesis through the alteration of the composition of NOTCH-dependent transcriptional complexes at selective NOTCH targets, such as HES5, including the recruitment of the deacetylase SIRT1 and resulting in an epigenetic silencing leading to neuronal differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 79 kDa

    Observed MW: 78 kDa The actual band is not consistent with the expectation.

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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