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Recombinant ABCE1 抗体

The 兔 单克隆 anti-ABCE1 antibody is suitable to detect ABCE1 in samples from 人 和 小鼠. It has been validated for WB 和 IF.
产品编号 ABIN7828031
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant ABCE1 抗体 (ABIN7828031)

抗原

See all ABCE1 抗体
ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

抗体类型

Recombinant Antibody

适用

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人, 小鼠

宿主

  • 59
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克隆类型

  • 46
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单克隆

标记

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This ABCE1 antibody is un-conjugated

应用范围

  • 52
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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

A119
  • 原理

    Recombinant ABCE1 Monoclonal Antibody

    纯化方法

    Protein A purified

    免疫原

    Recombinant human ABCE1 fragment

    亚型

    IgG, kappa
  • 应用备注

    WB 1:500-1:1000,IF 1:50

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

    别名

    ABCE1

    背景

    ABC,ABCE,RNASEL,OK/SW-cl,ABCE1,ABC38,OABP,RLI,RLI1,RNASEL1,RNASELI,RNS4I,OK/SW-cl.40,2' 5' oligoadenylate binding protein,2'5' oligoadenylate binding protein,2''-5''-oligoadenylate-binding protein,ABC 38,ABCE 1,ATP binding cassette sub family E (OABP) member 1,ATP binding cassette sub family E member 1,ATP-binding cassette sub-family E member 1,HuHP 68,HuHP68,Ribonuclease 4 inhibitor,Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor,Ribonuclease L inhibitor,RNase L inhibitor,RNS 4I,Cotranslational quality control factor involved in the No-Go Decay (NGD) pathway. Together with PELO and HBS1L, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes. Together with PELO and HBS1L, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs, this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway. Plays a role in the regulation of mRNA turnover. Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA. As part of the PINK1-regulated signaling, ubiquitinated by CNOT4 upon mitochondria damage, this modification generates polyubiquitin signals that recruit autophagy receptors to the mitochondrial outer membrane and initiate mitophagy. RNASEL-specific protein inhibitor which antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) to RNASEL. Negative regulator of the anti-viral effect of the interferon-regulated 2-5A/RNASEL pathway. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 34 kDa

    Observed MW: 45 kDa The actual band is not consistent with the expectation.

    UniProt

    P61221
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