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Recombinant ACLY 抗体

The 兔 单克隆 anti-ACLY antibody (Clone A772) (ABIN7828029) specifically detects ACLY in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7828029
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant ACLY 抗体 (ABIN7828029)

抗原

See all ACLY 抗体
ACLY (ATP Citrate Lyase (ACLY))

抗体类型

Recombinant Antibody

适用

  • 107
  • 44
  • 42
  • 9
  • 6
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 96
  • 14

克隆类型

  • 72
  • 38
单克隆

标记

  • 55
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This ACLY antibody is un-conjugated

应用范围

  • 91
  • 35
  • 28
  • 27
  • 27
  • 26
  • 21
  • 18
  • 11
  • 6
  • 6
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

A772
  • 原理

    Recombinant ATP Citrate Lyase Monoclonal Antibody

    纯化方法

    Protein A purified

    亚型

    IgG, kappa
  • 应用备注

    WB 1:1000,IHC 1:500

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

    有效期

    12 months
  • 抗原

    ACLY (ATP Citrate Lyase (ACLY))

    别名

    ATP Citrate Lyase

    背景

    OTTHUMP,ACLY,ACL,ATPCL,CLATP,ATP citrate (pro-S) lyase,ATP citrate lyase,ATP citrate synthase,ATP-citrate (pro-S-)-lyase,ATPcitrate synthase,ATP-citrate synthase,Citrate cleavage enzyme,OTTHUMP00000164773,ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and oxaloacetate (OAA) in the cytosol, which is the keystep for the biosynthesis of fatty acids, cholesterol and acetylcholine, as well as for glucogenesis. Nutrients and hormones regulate theexpression level and phosphorylation of ATP-citrate lyase. It is phosphorylated by GSK-3 on Thr446 and Ser450. Ser455 of ATP-citrate lyasehas been reported to be phosphorylated by PKA and Akt. Phosphorylation on Ser455 abolishes the homotropic allosteric regulation by citrateand enhances the catalytic activity of the enzyme. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

    分子量

    Calculated MW: 120 kDa

    Observed MW: 125 kDa The actual band is not consistent with the expectation.

    UniProt

    P53396

    途径

    Warburg Effect
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