Recombinant ATG9A 抗体
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北京 101111
Quick Overview for Recombinant ATG9A 抗体 (ABIN7828028)
抗原
See all ATG9A 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant ATG9A Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human ATG9A fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50,FCM 1:50-1:100
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))
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别名
- ATG9A
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背景
- MGD,mATG,APG9L,ATG9A,APG9L1,MGD3208,mATG9,APG9 autophagy 9-like 1,APG9 like 1,APG9-like 1,ATG9,ATG9 autophagy related 9 homolog A,ATG9 autophagy related 9 homolog A (S. cerevisiae),Autophagy 9-like 1 protein,Autophagy related 9A,Autophagy related protein 9A,Autophagy-related protein 9A,OTTHUMP00000206046,OTTHUMP00000206048,OTTHUMP00000206049,OTTHUMP00000206062,ATG9A are lipid scramblases that play a role in autophagosome expansion. ATG9A is present in numerous intracellular compartments, including the trans-Golgi network and early and recycling endosomes, and traffics through the secretory pathway to the plasma membrane and to the endocytic pathway from the plasma membrane. ATG9A protects cells against plasma membrane damage caused by a spectrum of exogenous and endogenous agents, including permeabilization by gasdermin and mixed lineage kinase domain like (MLKL), which generate pores at the plasma membrane or perturb plasma membrane integrity, respectively, during programmed cell death processes of pyroptosis and necroptosis. We furthermore define the ATG9A-IQGAP1 apparatus that integrates with the ESCRT system to cooperatively heal areas of plasma membrane damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 94 kDa
Observed MW: 100 kDa The actual band is not consistent with the expectation.
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UniProt
- Q7Z3C6
抗原
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