Recombinant ANGPTL3 抗体
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Quick Overview for Recombinant ANGPTL3 抗体 (ABIN7828020)
抗原
See all ANGPTL3 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant ANGPTL3 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Synthetic peptide derived from ANGPTL3 anti
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亚型
- IgG, kappa
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anti-Angiopoietin-Like 3 (ANGPTL3) antibody
ANGPTL3 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 17-460) antibodyANGPTL3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3B7 unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 21-120) antibodyANGPTL3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 22-281) antibodyANGPTL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 361-460) antibodyANGPTL3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F11 unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 271-491) antibodyANGPTL3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 270-490) antibodyANGPTL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 243-460) antibodyANGPTL3 适用: 人 WB, ELISA, ICC, IF 宿主: 小鼠 Monoclonal AT23D8 unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) antibodyANGPTL3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin-Like 3 (ANGPTL3) (AA 237-455) antibodyANGPTL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000,IHC 1:50-1:100,IF 1:50
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))
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别名
- ANGPTL3
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背景
- ANG,UNQ,PRO,FHBL,Angiopoietin,angiopoietin like,Angiopoietin-like protein,Angiopoietin-related protein,ANGPT,ANGPTL,ANGPTL3,ANG-5,ANGPT5,ANL3,FHBL2,angiopoietin like 3,Angiopoietin-5,Angiopoietin-like protein 3,Angiopoietin-related protein 3,ANL,UNQ153,PRO179,ANG-5,ANGPT5,ANL3,FHBL2,Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. Has a stimulatory effect on plasma triglycerides (TG), which is achieved by suppressing plasma TG clearance via inhibition of LPL activity. The inhibition of LPL activity appears to be an indirect mechanism involving recruitment of proprotein convertases PCSK6 and FURIN to LPL leading to cleavage and dissociation of LPL from the cell surface, the function does not require ANGPTL3 proteolytic cleavage but seems to be mediated by the N-terminal domain, and is not inhibited by GPIHBP1. Can inhibit endothelial lipase, causing increased plasma levels of high density lipoprotein (HDL) cholesterol and phospholipids. Can bind to adipocytes to activate lipolysis, releasing free fatty acids and glycerol. Suppresses LPL specifically in oxidative tissues which is required to route very low density lipoprotein (VLDL)-TG to white adipose tissue (WAT) for storage in response to food, the function may involve cooperation with circulating, liver-derived ANGPTL8 and ANGPTL4 expression in WAT. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 54 kDa
Observed MW: 54 kDa
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UniProt
- Q9Y5C1
抗原
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