Recombinant AFT1 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant AFT1 抗体 (ABIN7827998)
抗原
See all AFT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Recombinant ATF1 Monoclonal Antibody
-
纯化方法
- Protein A purified
-
免疫原
- Recombinant human ATF1 fragment
-
亚型
- IgG, kappa
-
-
-
-
应用备注
- WB 1:500-1:1000,IHC 1:100-1:1000,IF 1:50,FCM 1:50-1:100
-
限制
- 仅限研究用
-
-
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
-
有效期
- 12 months
-
-
- AFT1 (Activating Transcription Factor 1 (AFT1))
-
别名
- ATF1
-
背景
- ATF,Atf1,ATF-1 is a bZIP transcription factor that is a member of the cyclic AMP (cAMP)-response element-binding protein (CREB) family. Like other members of the CREB family, ATF-1 mediates signals from numerous physiological stimuli and activates target genes through cAMP-response elements, resulting in the regulation of a broad array of cellular responses. ATF-1 can be phosphorylated at Ser63 by protein kinase A (PKA), calmodulin-dependent protein kinase (CaMK), and cyclin-dependent kinase 3 (CDK3), which recruits CBP/p300 and enhances transcriptional activity. ATF-1 expression levels have been found to be elevated in lymphomas and metastatic melanoma cells, where it contributes to tumor growth. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
-
分子量
-
Calculated MW: 29 kDa
Observed MW: 35 kDa The actual band is not consistent with the expectation.
-
UniProt
- P81269
-
途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
抗原
-