Recombinant Aconitase 1 抗体
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Quick Overview for Recombinant Aconitase 1 抗体 (ABIN7827991)
抗原
See all Aconitase 1 (ACO1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Recombinant Aconitase 1/ACO1 Monoclonal Antibody
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Aconitase 1/ACO1 fragment
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亚型
- IgG, kappa
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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有效期
- 12 months
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- Aconitase 1 (ACO1)
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别名
- Aconitase 1/ACO1
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背景
- HEL,IRP,ACO,IREB,ACO1,ACONS,HEL60,IREB1,IREBP,IREBP1,IRP1,ACO 1,ACOC,Aconitase,Aconitase 1 soluble,Aconitase1,Aconitate hydratase,Citrate hydro lyase,Citrate hydro-lyase,Cytoplasmic aconitate hydratase,Ferritin repressor protein,IRE BP 1,IREB 1,IRE-BP 1,Iron regulatory protein 1,Iron responsive element binding protein 1,Iron-responsive element-binding protein 1,IRP 1,OTTHUMP00000045233,Aconitase 1 is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [
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分子量
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Calculated MW: 98 kDa
Observed MW: 105 kDa The actual band is not consistent with the expectation.
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UniProt
- P21399
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途径
- Transition Metal Ion Homeostasis
抗原
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