PHF8 抗体 (AA 108-946)
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北京 101111
Quick Overview for PHF8 抗体 (AA 108-946) (ABIN7825675)
抗原
See all PHF8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-946
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原理
- Anti-PHF8 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-PHF8 Antibody catalog # A03288-2. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PHF8 recombinant protein (Position: H108-D946). Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PHF8 (PHD Finger Protein 8 (PHF8))
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别名
- PHF8
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背景
- The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 140 kDa
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基因ID
- 23133
抗原
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