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Peroxiredoxin 4 抗体 (AA 167-260)

This 兔 多克隆 anti-Peroxiredoxin 4 antibody specifically detects Peroxiredoxin 4 in WB 和 IHC. The antibody is reactive with 斑马鱼 samples.
产品编号 ABIN7825670
发货至: 中国
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Quick Overview for Peroxiredoxin 4 抗体 (AA 167-260) (ABIN7825670)

抗原

See all Peroxiredoxin 4 (PRDX4) 抗体
Peroxiredoxin 4 (PRDX4)

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This Peroxiredoxin 4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 167-260

    原理

    Anti-Zebrafish PRDX4 Antibody

    产品特性

    Anti-Zebrafish PRDX4 Antibody catalog # AZA3KP44. Tested in WB, IHC applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived zebrafish PRDX4 recombinant protein (Position: S167-N260).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Zebrafish
    Immunohistochemistry, 2-5 μg/mL, Zebrafish

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    Peroxiredoxin 4 (PRDX4)

    别名

    PRDX4

    背景

    PRDX4 (peroxiredoxin 4) is also known as AOE37-2. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. Functional analysis showed that PRDX4 protects glutamine synthetase from inactivation. Yeast 2-hybrid, immunoprecipitation, and immunoblot analyses indicated that PRDX4 and PRDX1 are capable of homodimerization and heterodimerization with each other but not with the mitochondrial PRDX3. Gel mobility shift and immunoblot analysis found that PRDX4 depletes NFKB binding activity together with a reduction in the amounts of p50, p65, and phosphorylated IKBA, as well as a reduction in the expression of HIV-1 viral proteins. Expression of PRDX4, alone or with PRDX1, increased the resistance of yeast cells to oxidant-induced toxicity. Jin et al. suggested PRDX4 modulates IKBA phosphorylation in the cytoplasm and thus affects a peroxiredoxin-dependent redox step.

    分子量

    27 kDa
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