PDX1 抗体 (AA 1-246)
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北京 101111
Quick Overview for PDX1 抗体 (AA 1-246) (ABIN7825654)
抗原
See all PDX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-246
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原理
- Anti-Zebrafish PDX1 Antibody
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产品特性
- Anti-Zebrafish PDX1 Antibody catalog #AZQ6DC85. Tested in WB applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived zebrafish PDX1 recombinant protein (Position: M1-S246)
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Zebrafish
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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别名
- PDX1
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背景
- PDX1 (pancreatic and duodenal homeobox 1), also known as insulin promoter factor 1, is a transcription factor in the ParaHox gene cluster. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
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分子量
- 38 kDa
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
抗原
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