PPP1R12A 抗体 (AA 1-40)
Our Local Distributor
北京 101111
Quick Overview for PPP1R12A 抗体 (AA 1-40) (ABIN7825566)
抗原
See all PPP1R12A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-40
-
原理
- Anti-Zebrafish MYPT1/PPP1R12A Antibody
-
产品特性
- Anti-Zebrafish MYPT1/PPP1R12A Antibody catalog # AZQ6DRG7. Tested in WB, IHC applications. This antibody reacts with Zebrafish. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived zebrafish MYPT1/PPP1R12A recombinant protein (Position: M1-D40).
-
亚型
- IgG
-
-
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 1-200) antibody
PPP1R12A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (C-Term) antibodyVerified PPP1R12A 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 1-40), (N-Term) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (C-Term) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr696) antibodyPPP1R12A 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr853) antibodyPPP1R12A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 710-970) antibodyPPP1R12A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 481-514), (Ser507) antibodyPPP1R12A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56872 unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr853) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pSer696) antibodyPPP1R12A 适用: 人, 小鼠, 大鼠, 斑马鱼, 小鸡, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Zebrafish
Immunohistochemistry, 2-5 μg/mL, Zebrafish
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))
-
别名
- PPP1R12A
-
背景
- PPP1R12A (Protein phosphatase 1 regulatory subunit 12A), also called MYPT1 (Myosin phosphatase target subunit 1), is an enzyme that in humans is encoded by the PPP1R12A gene. PPP1R12A is one of the subunits of myosin phosphatase. Sequencing analysis showed that human PPP1R12A contains 1,030 amino acids with a calculated molecular mass of approximately 115 kD. The PPP1R12A gene is mapped on 12q21.2-q21.3. PPP1R12A is the protein that regulates PP1 function in smooth muscle relaxation. The cellular MYPT1-PP1-delta -specific inhibitor CPI17 caused a loss of merlin function characterized by merlin phosphorylation, Ras activation, and transformation. Jin et al. concluded that PPP1R12A and its substrate merlin are part of a previously undescribed tumor suppressor cascade that can be hindered in two ways, by mutation of the NF2 gene and by upregulation of the oncoprotein CPI17.
-
分子量
- 140 kDa
-
途径
- M Phase
抗原
-
