IMPA1 抗体 (AA 1-277)
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北京 101111
Quick Overview for IMPA1 抗体 (AA 1-277) (ABIN7825474)
抗原
See all IMPA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-277
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原理
- Anti-IMPA1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IMPA1 Antibody catalog # A05882-2. Tested in WB, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IMPA1 recombinant protein (Position: M1-D277). Human IMPA1 shares 86.6% and 85.1% amino acid (aa) sequence identity with mouse and rat IMPA1, respectively.
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亚型
- IgG
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anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibody
IMPA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) antibodyIMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 小鼠 Monoclonal AT2G5 unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) antibodyIMPA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (AA 1-277) antibodyIMPA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6-F11 unconjugated
anti-Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1) (C-Term) antibodyIMPA1 适用: 人, 小鼠, 大鼠, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IMPA1 (Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
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别名
- IMPA1
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背景
- This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
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分子量
- 30 kDa
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基因ID
- 3612
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UniProt
- P29218
抗原
-
