ING3 抗体 (AA 1-367)
Our Local Distributor
北京 101111
Quick Overview for ING3 抗体 (AA 1-367) (ABIN7825472)
抗原
See all ING3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-367
-
原理
- Anti-ING3 Antibody
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-ING3 Antibody catalog # A05458-2. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human ING3 recombinant protein (Position: M1-Q367). Human ING3 shares 95.1% and 96.5% amino acid (aa) sequence identity with mouse and rat ING3, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- ING3 (Inhibitor of Growth Family, Member 3 (ING3))
-
别名
- ING3
-
背景
- The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
-
分子量
- 47 kDa
-
基因ID
- 54556
抗原
-