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FOXM1 抗体 (AA 457-760)

This anti-FOXM1 antibody is a 兔 多克隆 antibody detecting FOXM1 in WB, ELISA, IHC 和 IP. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7825381
发货至: 中国

Quick Overview for FOXM1 抗体 (AA 457-760) (ABIN7825381)

抗原

See all FOXM1 抗体
FOXM1 (Forkhead Box M1 (FOXM1))

适用

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人, 大鼠, 小鼠

宿主

  • 42
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克隆类型

  • 39
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多克隆

标记

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This FOXM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • 抗原表位

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    AA 457-760

    原理

    Anti-FOXM1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-FOXM1 Antibody catalog # A00659-2. Tested in WB, IHC, ELISA, IP applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FOXM1 recombinant protein (Position: Q457-P760).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human
    Immunoprecipitation, 0.5-2 μg/mL, Human
    ELISA, 0.1-0.5 μg/m, -l

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    FOXM1 (Forkhead Box M1 (FOXM1))

    别名

    FOXM1

    背景

    Forkhead box protein M1, also called FOXM1, is a protein that in humans is encoded by the FOXM1 gene. It is mapped to 12p13.33. The protein encoded by this gene is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It was hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. What's more, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 brain washes normal cells to adopt cancer-like epigenome.

    分子量

    100-110 kDa

    UniProt

    Q08050

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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