DOCK3 抗体 (AA 88-2006)
The 兔 多克隆 anti-DOCK3 antibody is suitable to detect DOCK3 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, WB, IHC 和 FACS.
产品编号 ABIN7825336
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for DOCK3 抗体 (AA 88-2006) (ABIN7825336)
抗原
See all DOCK3 抗体
DOCK3
(Dedicator of Cytokinesis 3 (DOCK3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DOCK3 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
-
-
抗原表位
- AA 88-2006
-
原理
- Anti-MOCA/DOCK3 Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-MOCA/DOCK3 Antibody catalog # A08904. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human MOCA/DOCK3 recombinant protein (Position: E88-K2006). Human MOCA/DOCK3 shares 98% amino acid (aa) sequence identity with mouse MOCA/DOCK3.
-
亚型
- IgG
-
-
anti-Dedicator of Cytokinesis 3 (DOCK3) (AA 1630-1934) antibody
DOCK3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
-
别名
- DOCK3
-
背景
- This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement.
-
分子量
- 233 kDa
-
基因ID
- 1795
抗原
-
You are here:
