DOCK3 抗体 (AA 88-2006)
This anti-DOCK3 antibody is a 兔 多克隆 antibody detecting DOCK3 in ELISA, WB, IHC 和 FACS. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for DOCK3 抗体 (AA 88-2006) (ABIN7825336)
抗原
See all DOCK3 抗体
DOCK3
(Dedicator of Cytokinesis 3 (DOCK3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DOCK3 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
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抗原表位
- AA 88-2006
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原理
- Anti-MOCA/DOCK3 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MOCA/DOCK3 Antibody catalog # A08904. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MOCA/DOCK3 recombinant protein (Position: E88-K2006). Human MOCA/DOCK3 shares 98% amino acid (aa) sequence identity with mouse MOCA/DOCK3.
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亚型
- IgG
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anti-Dedicator of Cytokinesis 3 (DOCK3) (AA 1630-1934) antibody
DOCK3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
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别名
- DOCK3
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背景
- This gene is specifically expressed in the central nervous system (CNS). It encodes a member of the DOCK (dedicator of cytokinesis) family of guanine nucleotide exchange factors (GEFs). This protein, dedicator of cytokinesis 3 (DOCK3), is also known as modifier of cell adhesion (MOCA) and presenilin-binding protein (PBP). The DOCK3 and DOCK1, -2 and -4 share several conserved amino acids in their DHR-2 (DOCK homology region 2) domains that are required for GEF activity, and bind directly to WAVE proteins [Wiskott-Aldrich syndrome protein (WASP) family Verprolin-homologous proteins] via their DHR-1 domains. The DOCK3 induces axonal outgrowth in CNS by stimulating membrane recruitment of the WAVE complex and activating the small G protein Rac1. This gene is associated with an attention deficit hyperactivity disorder-like phenotype by a complex chromosomal rearrangement.
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分子量
- 233 kDa
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基因ID
- 1795
抗原
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