CAMKK2 抗体 (AA 1-349)
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北京 101111
Quick Overview for CAMKK2 抗体 (AA 1-349) (ABIN7825298)
抗原
See all CAMKK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-349
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原理
- Anti-CAMKK2 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-CAMKK2 Antibody catalog # A03048. Tested in WB, IHC, IF, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CAMKK2 recombinant protein (Position: M1-G349).
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亚型
- IgG
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anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-130) antibody
CAMKK2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A11 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 1-541) antibodyCAMKK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (C-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibodyKO Validated CAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512), (C-Term) antibodyCAMKK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12560 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (N-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠, Pig, 豚鼠, Cow, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) antibodyCAMKK2 适用: 人, 小鼠 WB, ELISA 宿主: 小鼠 Monoclonal 239CT7-5-3 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 52-82) antibodyCAMKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 483-512) antibodyCAMKK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2) (AA 43-71), (N-Term) antibodyCAMKK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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别名
- CAMKK2
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背景
- CAMKK2, Calcium/calmodulin-dependent protein kinase kinase 2, is an enzyme that in humans is encoded by the CAMKK2 gene. The product of this gene belongs to the serine/threonine-specific protein kinase family, and to the Ca++/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent(CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. CaMKK2 regulates production of the appetite stimulating hormone neuropeptide Y and functions as an AMPK kinase in the hypothalamus. It also has an important role in the development of hyperalgesia and tolerance to opioid analgesic drugs, through reduction in downstream signalling pathways and mu opioid receptor downregulation. Inhibition of CaMKK2 in mice reduces appetite and promotes weight loss.
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分子量
- 65 kDa
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途径
- AMPK Signaling
抗原
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