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AXIN2 抗体 (AA 86-812)

The 兔 多克隆 anti-AXIN2 antibody (ABIN7825283) specifically detects AXIN2 in IHC. The antibody is reactive with 斑马鱼 samples.
产品编号 ABIN7825283
发货至: 中国
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Quick Overview for AXIN2 抗体 (AA 86-812) (ABIN7825283)

抗原

See all AXIN2 抗体
AXIN2 (Axin 2 (AXIN2))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This AXIN2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    AA 86-812

    原理

    Anti-Zebrafish AXIN2 Antibody

    产品特性

    Anti-Zebrafish AXIN2 Antibody catalog #AZP57095. Tested in IHC applications. This antibody reacts with Zebrafish.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived zebrafish AXIN2 recombinant protein (Position: H86-D812)

    亚型

    IgG
  • 应用备注

    Immunohistochemistry, 2-5 μg/mL, Zebrafish

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    AXIN2 (Axin 2 (AXIN2))

    别名

    AXIN2

    背景

    Axin-2 also known as axin-like protein (Axil) or axis inhibition protein 2 (AXIN2) or conductin is a protein that in humans is encoded by the AXIN2 gene. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.

    UniProt

    P57095

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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