PVRL4 抗体
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北京 101111
Quick Overview for PVRL4 抗体 (ABIN7822916)
抗原
See all PVRL4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- PVRL4 Antibody / Nectin-4
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 1-200 from the human protein was used as the immunogen for the PVRL4 antibody.
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亚型
- IgG2a, kappa
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anti-Poliovirus Receptor-Related 4 (PVRL4) antibody
PVRL4 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 91-199) antibodyPVRL4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 151-250) antibodyPVRL4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (Internal Region) antibodyPVRL4 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 84-96), (Extracellular) antibodyPVRL4 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 371-510) antibodyPVRL4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 31-139) antibodyPVRL4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 1-510) antibodyPVRL4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 4 (PVRL4) antibodyPVRL4 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
anti-Poliovirus Receptor-Related 4 (PVRL4) (AA 31-317) antibodyPVRL4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (FFPE): 1-2ug/ml
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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储存液
- Sodium azide
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- Aliquot the PVRL4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
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- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
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别名
- Poliovirus Receptor-Related 4
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背景
- Homologous to the poliovirus receptor (PVR/CD155), the nectin immunoglobulin superfamily comprises four known isoforms (-1, -2, -3, and -4). The ectodomain of nectin family members comprises three Ig-like domains (V, C, C). Nectins localize at the adherens junctions (AJ) in epithelial and endothelial cells where they serve as adhesion molecules. Actin-based AJs play a role in mechanical adhesion, cellular morphogenesis and cellular differentiation. Nectin associates with the actin cytoskeleton through its interaction with the actin filament-binding protein afadin. Nectin 4 and afadin co-localize at cadherin-based adherens junctions in MDCKII epithelial cells. Nectin 4 and nectin 3 share a common binding region in the V domain of Nectin 1 and thus compete for Nectin 1 binding. The Nectin 3/4 binding domain maps to the C-C strands of the V domain of Nectin 1. Unlike other nectins, which are more widely expressed, Nectin 4 is mainly expressed in the placenta.
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UniProt
- Q96NY8
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途径
- Cell-Cell Junction Organization
抗原
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