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ADRP 抗体 (AA 31-130)

This anti-ADRP antibody is a 兔 多克隆 antibody detecting ADRP in WB, ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN738606
发货至: 中国

Quick Overview for ADRP 抗体 (AA 31-130) (ABIN738606)

抗原

See all ADRP (PLIN2) 抗体
ADRP (PLIN2) (Perilipin 2 (PLIN2))

适用

  • 135
  • 20
  • 12
  • 2
人, 小鼠

宿主

  • 74
  • 56
  • 5
  • 1

克隆类型

  • 77
  • 59
多克隆

标记

  • 60
  • 11
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ADRP antibody is un-conjugated

应用范围

  • 87
  • 71
  • 41
  • 34
  • 31
  • 23
  • 19
  • 13
  • 13
  • 12
  • 9
  • 6
  • 4
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  • 3
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  • 2
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  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 52
    • 15
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-130

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from rat ADFP

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Zhao, Han, Hong, Sun: "Adipose differentiation‑related protein knockdown inhibits vascular smooth muscle cell proliferation and migration and attenuates neointima formation." in: Molecular medicine reports, Vol. 16, Issue 3, pp. 3079-3086, (2018) (PubMed).

    Amrutkar, Cansby, Nuñez-Durán, Pirazzi, Ståhlman, Stenfeldt, Smith, Borén, Mahlapuu: "Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 4, pp. 1564-76, (2015) (PubMed).

    Amrutkar, Cansby, Chursa, Nuñez-Durán, Chanclón, Ståhlman, Fridén, Mannerås-Holm, Wickman, Smith, Bäckhed, Borén, Howell, Mahlapuu: "Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes Model." in: Diabetes, Vol. 64, Issue 8, pp. 2791-804, (2015) (PubMed).

    Liu, Dai, Liu, Liu, Tang, Wang, Yi, Liu, Jiang, Yang, Yuan: "Oxidized low-density lipoprotein activates adipophilin through ERK1/2 signal pathway in RAW264.7 cells." in: Acta biochimica et biophysica Sinica, Vol. 42, Issue 9, pp. 635-45, (2010) (PubMed).

  • 抗原

    ADRP (PLIN2) (Perilipin 2 (PLIN2))

    别名

    ADFP

    背景

    Synonyms: ADFP, Adipophilin, Adipose dferentiation related protein, Adipose dferentiation-related protein, Perilipin-2, PLIN2, PLIN2_HUMAN, adipophilin, Adipose dferentiation related protein, ADRP, MGC10598

    Background: Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP) associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, was a major constituent of the globule surface and was present in a detergent-insoluble complex that contained stoichiometric amounts of butyrophilin and xanthine oxidase. ADFP (Adipophilin) occurs in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to certain cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.

    基因ID

    298199

    途径

    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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