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Cyclin D2 抗体 (AA 161-288)

Name: Cyclin D2 抗体 (AA 161-288)
SKU: ABIN738366
Availability: OutOfStock

This anti-Cyclin D2 antibody is a 兔多克隆 antibody detecting Cyclin D2 in WB, ELISA, FACS, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Formalin-fixed and paraffin embedded human flat moss tinea tissue labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated (ABIN738366) at 1:200 followed by conjugation to the secondary antibody and DAB staining (Cyclin D2 抗体 (AA 161-288))

IHC

Formalin-fixed and paraffin embedded rat ovary labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (Cyclin D2 抗体 (AA 161-288))

IHC (p)

Formalin-fixed and paraffin embedded rat ovary labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated (ABIN738366) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (Cyclin D2 抗体 (AA 161-288))

IHC

Image provided by One World Lab validation program. (Cyclin D2 抗体 (AA 161-288))

IF (cc)

Formalin-fixed and paraffin embedded human flat moss tinea tissue labeled with Anti-Cyclin D2 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (Cyclin D2 抗体 (AA 161-288))

IHC (p)

6 images

(1 reference)

产品编号 ABIN738366

发货至: 中国

Quick Overview for Cyclin D2 抗体 (AA 161-288) (ABIN738366)

抗原

See all Cyclin D2 (CCND2) 抗体

Cyclin D2 (CCND2)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Cyclin D2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

抗原表位
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7

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2

2

2

2

1

1

1
AA 161-288

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Cyclin D2

亚型

IgG
anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 47-267) antibody
CCND2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 68-278) antibody
CCND2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 1-289) antibody
CCND2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) (AA 215-285) antibody
CCND2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D2 (CCND2) antibody
CCND2 适用: 人 ELISA, Coat 宿主: 小鼠 Monoclonal CCND2-2620 unconjugated

anti-Cyclin D2 (CCND2) (AA 190-289) antibody
CCND2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B10 unconjugated

anti-Cyclin D2 (CCND2) (pThr280) antibody
CCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Wu, Gao, Chen, Gu, Ding, Guo: "Elevated toll-like receptor 3 inhibits pancreatic ?-cell proliferation through G1 phase cell cycle arrest." in: Molecular and cellular endocrinology, Vol. 377, Issue 1-2, pp. 112-22, (2013) (PubMed).
抗原

Cyclin D2 (CCND2)

别名

Cyclin D2

背景

Synonyms: MPPH3, KIAK2, G1/S-specific cyclin-D2, CCND2
Background: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).

基因ID

894

UniProt

P30279

途径

Cell Division Cycle, Mitotic G1-G1/S Phases