我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

CADM1 抗体 (AA 365-442)

Name: CADM1 抗体 (AA 365-442)
SKU: ABIN738351
Availability: OutOfStock

This anti-CADM1 antibody is a 兔多克隆 antibody detecting CADM1 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人和大鼠. This Primary Antibody has been cited in 2+ publications.

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-SynCAM/TSLC1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CADM1 抗体 (AA 365-442))

IHC (p)

L1 rat brain lysates, L2 rat heart lysates probed (ABIN738351) Anti-SynCAM/TSLC1 Polyclonal, Unconjugated at 1:200 in 4 °C. (CADM1 抗体 (AA 365-442))

SDS

Formalin-fixed and paraffin embedded human cervical carcinoma tissue labeled with Anti-SynCAM/TSLC1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (CADM1 抗体 (AA 365-442))

IHC (p)

3 images

(2 references)

产品编号 ABIN738351

发货至: 中国

Quick Overview for CADM1 抗体 (AA 365-442) (ABIN738351)

抗原

See all CADM1 抗体

CADM1 (Cell Adhesion Molecule 1 (CADM1))

适用

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CADM1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product CADM1 Primary Antibody

抗原表位
16

10

8

5

4

3

3

2

2

2

2

2

1

1

1

1

1
AA 365-442

交叉反应

人, 大鼠

预测反应

Mouse,Dog,Chicken

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human TSLC1

亚型

IgG
anti-Cell Adhesion Molecule 1 (CADM1) (AA 151-250) antibody
CADM1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (Internal Region) antibody
CADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (AA 65-160) antibody
CADM1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibody
CADM1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibody
CADM1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (C-Term) antibody
CADM1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (AA 27-292) antibody
CADM1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (AA 45-344) antibody
CADM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (AA 66-94), (N-Term) antibody
CADM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB22685 unconjugated

anti-Cell Adhesion Molecule 1 (CADM1) (AA 69-98), (N-Term) antibody
CADM1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: "Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ..." in: Toxicology and applied pharmacology, Vol. 251, Issue 1, pp. 70-8, (2011) (PubMed).
抗原

CADM1 (Cell Adhesion Molecule 1 (CADM1))

别名

TSLC1

背景

Synonyms: BL2, ST17, IGSF4, NECL2, RA175, TSLC1, IGSF4A, Necl-2, SYNCAM, sgIGSF, sTSLC-1, synCAM1, Cell adhesion molecule 1, Immunoglobulin superfamily member 4, Nectin-like protein 2, Spermatogenic immunoglobulin superfamily, Synaptic cell adhesion molecule, Tumor suppressor in lung cancer 1, TSLC-1, CADM1
Background: Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

基因ID

23705

UniProt

Q9BY67

途径

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation