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CHI3L1 抗体 (AA 330-381)

This anti-CHI3L1 antibody is a 兔 多克隆 antibody detecting CHI3L1 in WB, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN737556
发货至: 中国

Quick Overview for CHI3L1 抗体 (AA 330-381) (ABIN737556)

抗原

See all CHI3L1 抗体
CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

适用

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人, 小鼠, 大鼠

宿主

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  • 13
  • 1
  • 1

克隆类型

  • 51
  • 12
  • 2
多克隆

标记

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  • 2
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  • 2
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  • 2
  • 1
  • 1
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This CHI3L1 antibody is un-conjugated

应用范围

  • 47
  • 23
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  • 7
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 330-381

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from rat CGP-39/CHI3L1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Ben, Qiu, Zhou, Zhou, Zhang, Wu, Ju, Ni: "Ovalbumin enhances YKL-40, IL-5, GM-CSF, and eotaxin expression simultaneously in primarily cultured mouse tracheal epithelial cells." in: In vitro cellular & developmental biology. Animal, Vol. 50, Issue 3, pp. 243-50, (2014) (PubMed).

    Tanaka, Matsumoto, Inoue, Umeda, Takai, Sumida: "Antigen-specific over-expression of human cartilage glycoprotein 39 on CD4+ CD25+ forkhead box protein 3+ regulatory T cells in the generation of glucose-6-phosphate isomerase-induced arthritis." in: Clinical and experimental immunology, Vol. 177, Issue 2, pp. 419-27, (2014) (PubMed).

  • 抗原

    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

    别名

    CHI3L1

    背景

    Synonyms: Chitinase-3-like protein 1, Cartilage glycoprotein 39, CGP-39, GP-39, Chi3l1

    Background: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).

    分子量

    42kDa

    基因ID

    89824
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