Oct-2 抗体 (AA 11-100)
Quick Overview for Oct-2 抗体 (AA 11-100) (ABIN737316)
抗原
See all Oct-2 (POU2F2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-100
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交叉反应
- 人, 小鼠
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预测反应
- Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse OCT2
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Macrophage polarization in human gingival tissue in response to periodontal disease." in: Oral diseases, Vol. 25, Issue 1, pp. 265-273, (2019) (PubMed).
: "The Altered Renal and Hepatic Expression of Solute Carrier Transporters (SLCs) in Type 1 Diabetic Mice." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120760, (2015) (PubMed).
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: "Macrophage polarization in human gingival tissue in response to periodontal disease." in: Oral diseases, Vol. 25, Issue 1, pp. 265-273, (2019) (PubMed).
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- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
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别名
- 2-Oct
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背景
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Synonyms: Otf2, Oct-2, Oct2a, Oct2b, Otf-2, POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Pou2f2, Oct2
Background: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
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基因ID
- 18987
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UniProt
- Q00196
抗原
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