Recombinant NF-KappaB2 (/p52) (AA 1-50) 抗体
The 兔 单克隆 anti-NF-KappaB2 (/p52) antibody is suitable to detect NF-KappaB2 (/p52) in samples from 人. It has been validated for FACS, ICC, IHC, IP 和 WB.
产品编号 ABIN7795782
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Recombinant NF-KappaB2 (/p52) (AA 1-50) 抗体 (ABIN7795782)
抗原
NF-KappaB2 (/p52)
抗体类型
Recombinant Antibody
适用
人
宿主
兔
克隆类型
单克隆
应用范围
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
克隆位点
BLR350N
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抗原表位
- AA 1-50
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原理
- Rabbit anti-NF-kappaB2 (p100/p52) Recombinant Monoclonal Antibody [BLR350N]
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纯化方法
- Purified
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免疫原
- between 1 and 50
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亚型
- IgG
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应用备注
- WB,11000,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate,Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 1 μL per 1 x 10^6 cells.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- NF-KappaB2 (/p52)
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背景
- The NFKB2 gene encodes a 100 kDa protein that can undergo co-translational processing to also yield a 52 kDa protein. The 52 kDa protein is also known as NF-kappa B2/p52 and is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The 100 kDa product is also known as p100 or I kappa B delta. P100/I kappa B delta has been shown to function as an inhibitor protein that interacts with NF-kappa B and inhibit its DNA binding activity. P100/I kappa B delta is a member of the I kappa B family of proteins which includes I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa B1/p105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. The classical description of the NF-kappa B transcription factor is a transcription factor that reprograms gene expression of the immune system in response to injury, infection, and stress.
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基因ID
- 4791
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UniProt
- Q00653
抗原
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