IL5
适用: 人
FACS
宿主: 兔
Chimeric
unconjugated
Fc fragment
应用备注
WB,11000
限制
仅限研究用
状态
Liquid
浓度
1000 μg/mL
缓冲液
Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
2 - 8 °C
有效期
12 months
抗原
IL-5 (IL5)
(Interleukin 5 (IL5))
别名
IL-5
背景
IL-5 is a homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. IL-5 also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. IL-5 exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P05113].