Recombinant IL-4 抗体 (AA 25-153)
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Quick Overview for Recombinant IL-4 抗体 (AA 25-153) (ABIN7795704)
抗原
See all IL-4 (IL4) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 25-153
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原理
- Rabbit anti-IL-4 Recombinant Monoclonal Antibody [BLR298L] - BSA-Free
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纯化方法
- Purified
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免疫原
- Residues 25-153
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1000 μg/mL
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缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2 - 8 °C
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有效期
- 12 months
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- IL-4 (IL4) (Interleukin 4 (IL4))
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别名
- IL-4
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背景
- IL-4 is a pleiotropic cytokine produced by activated T cells. It acts by binding to the interleukin 4 receptor and STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. IL-4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4, a type 2 cytokine, mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation. In an allergic response, IL-4 has an essential role in the production of allergen-specific immunoglobin (Ig) E. [provided by RefSeq, Aug 2020] [taken from NCBI Entrez Gene (Gene ID: 3565)].
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基因ID
- 3565
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UniProt
- P05112
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
抗原
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